Final answer:
Manifestations of NSAID toxicity include nausea, vomiting, abdominal pain, constipation, and cardiovascular abnormalities. Severe cases can result in more critical symptoms such as seizures and shock. NSAIDs carry risks of stomach bleeding and kidney damage, especially in certain high-risk groups.
Step-by-step explanation:
The nurse recognizes that manifestations of NSAID toxicity would include nausea and vomiting. Nonsteroidal anti-inflammatory drugs (NSAIDs) have a range of side effects which can be indicative of toxicity, particularly when taken in excess or by individuals with certain risk factors. Some of the symptoms associated with NSAID toxicity include nausea, vomiting, abdominal pain, constipation cardiovascular abnormalities, dizziness, fever, chills and headache.
Severe cases may also result in jaundice, rash, mucosal hemorrhaging, seizures, shock, and even death. Regular use of NSAIDs increases the risk of stomach bleeding particularly in those over the age of 60, on blood thinners, steroids or with a history of stomach bleeding or ulcers. In addition, NSAIDs can lead to kidney damage especially in individuals with pre-existing conditions or those over 60. While aspirin a commonly used NSAID, inhibits blood clot formation it can result in gastrointestinal ulcers and bleeding, heart attack, and kidney disease when misused.