Final answer:
The schedule of drugs with the highest potential for abuse is Schedule I, which includes substances like heroin, LSD, marijuana, and ecstasy, leading to severe addiction and health risks.
Step-by-step explanation:
The schedule of drugs with the highest potential for abuse is Schedule I. These drugs are classified as having a high potential for abuse, no currently accepted medical use in treatment in the United States, and a lack of accepted safety for use under medical supervision. Examples of Schedule I substances include heroin, LSD, marijuana (cannabis), and ecstasy (MDMA). The abuse of these drugs may lead to severe psychological or physical dependence. Drug schedules are categorized by the United States Drug Enforcement Administration (DEA) from Schedule I to Schedule V, with Schedule I drugs being the most dangerous and Schedule V the least in terms of abuse potential. The problem of drug abuse, particularly with opioids such as fentanyl, oxycodone, and heroin, is a significant health issue, as evidenced by drug overdoses and the aggressive policing of pill mills.