Final answer:
During an inflammatory response, pale cold skin is the least likely occurrence at the site of injury due to the increased blood flow that causes redness, heat, and swelling.
Step-by-step explanation:
During an inflammatory response to injury, the least likely occurrence in the region of the injury is d) pale cold skin. This is because the inflammatory response involves an increase in blood flow to the area, caused by vasodilation (expansion) of blood vessels. This vasodilation brings more blood to the injured area, causing classic symptoms such as redness, heat, and swelling. Increased blood flow, along with the activity of phagocytes, like neutrophils and macrophages, is a central part of the body's response to inflammation, which refutes the presence of pale, cold skin at the site of injury.