Final answer:
The two types of I/O Addressing in ECE 385 are Memory-Mapped I/O, where I/O device registers are part of the memory space, and Isolated I/O, which has a separate I/O address space.
Step-by-step explanation:
The two major types of I/O Addressing covered in ECE 385 are Memory-Mapped I/O and Isolated I/O. Memory-Mapped I/O integrates I/O device registers as part of the memory space, so both memory and I/O devices are accessed using the same address bus. This type of addressing can simplify programming because it allows the same instructions that are used for memory operations to also be used for I/O operations. However, it requires part of the memory address space to be allocated for I/O devices.
In contrast, Isolated I/O, also known as Port-Mapped I/O, allocates a separate address space for I/O, so it requires separate instructions to access I/O devices. While this might necessitate a more complex set of instructions, it allows for a more extensive memory space for the actual memory. Therefore, each type of I/O addressing has its advantages and is chosen based on the specific needs of the computer architecture and software.