Final answer:
The respiratory therapist should decrease the inspiratory pressure to address over-distension indicated by the pressure-volume waveform in a patient being ventilated with PC, SIMV in the ICU.
Step-by-step explanation:
If a patient in the ICU being ventilated with PC, SIMV is showing a high inspiratory pressure of 62 cm H2O, an SpO2 of 92%, and a PETCO2 of 25 torr, and the pressure-volume waveform indicates over-distension, the respiratory therapist should consider decreasing the inspiratory pressure. This action would reduce the risk of lung injury due to over-distension and might also improve oxygenation and ventilation by allowing more efficient gas exchange. It's important to note that adjusting ventilator settings requires careful monitoring and assessment of the patient's clinical status, including the observation of SpO2 and PETCO2 levels, to ensure the changes are beneficial.