Final answer:
Thiazide diuretics share the common side effect of increased urination due to their mechanism of reducing the reabsorption of sodium and chloride in the distal convoluted tubule, leading to more water being excreted.
Step-by-step explanation:
The common side effect that all thiazide diuretics have is an increase in urination. Thiazide diuretics are a class of medications commonly used to treat high blood pressure and fluid retention. They work by inhibiting the reabsorption of sodium (Na+) and chloride (Cl-) ions in the distal convoluted tubule of the kidney. This inhibition leads to an increase in the excretion of sodium, which osmotically draws water into the renal tubules, escalating urine formation and output (diuresis).
Examples of thiazide diuretics include Chlorothiazide (Diuril), Chlorthalidone (Hygroton), and Hydrochlorothiazide (Esidrix, Hydrodiuril). These drugs are different from loop diuretics like Furosemide (Lasix), which act on the loop of Henle, though they still share the common side effect of increased urination.