Final answer:
Apaf1 and cytochrome c rearrange to activate caspases and initiate apoptosis.
Step-by-step explanation:
Apoptotic Protease Activating Factor 1 (Apaf1) and cytochrome c are involved in the process of apoptosis, which is programmed cell death. When there is cellular damage or stress, cytochrome c is released from the mitochondria into the cytosol. Once in the cytosol, cytochrome c binds to Apaf1, along with other proteins, forming the apoptosome complex. This complex then activates a series of caspases, which are proteolytic enzymes that initiate cell death. Therefore, the subsequent rearrangement of Apaf1 + Cytochrome c results in caspase activation and apoptosis.