Final answer:
Activated vitamin D (calcitriol) plays a central role in bone mineral metabolism by increasing calcium and phosphorus absorption from the intestines, enhancing renal reabsorption of calcium, and working with PTH to manage calcium levels in the bones.
Step-by-step explanation:
Role of Activated Vitamin D (Calcitriol) in Bone Mineral Metabolism Disorder (BMMD-2)
Vitamin D is crucial for the maintenance and balance of calcium within the body, which is essential for bone health and a range of physiological functions. The synthesis of vitamin D starts with the conversion of cholesterol to cholecalciferol (Vitamin D3). After a series of transformations in the liver and kidneys, the final product is calcitriol, the active form of vitamin D, which is significant in bone mineral metabolism.
Calcitriol performs several functions critical for maintaining calcium homeostasis:
- Without adequate levels of Vitamin D3 and its metabolite, calcitriol, healthy bone mineralization cannot occur, leaving individuals at risk for disorders such as osteoporosis, osteomalacia, and rickets.