Final answer:
British interference with US affairs, including the impressment of American sailors, led to the War of 1812, a conflict that arose from unresolved issues post-American Revolutionary War and the desire to uphold American sovereignty and honor.
Step-by-step explanation:
The interference of the British with US affairs, particularly the impressment (or kidnapping) of around 6,000 sailors, led to a significant conflict known as the War of 1812. This conflict is often referred to as the Second War of American Independence and was fueled by unresolved tensions following the American Revolutionary War. The British practice of impressment, the seizure of American ships, and the support of Native Americans against US territorial expansion triggered American ire and eventually led to war. Notably, the incident involving the HMS Leopard and the USS Chesapeake in 1807, where the British warship fired upon and boarded the American vessel to forcibly remove purported deserters, incensed the American public and politicians alike. The event, coupled with the economic strain caused by the Embargo Act of 1807, which was an attempt to compel Britain and France to respect American neutrality on the high seas, escalated to a call to arms. After much debate and division within the US government, Congress declared war on Britain in June 1812.