Final answer:
Acne caused by a bacterial infection affects the stratum corneum layer of the epidermis, which is the most superficial layer. This layer consists of dry, dead cells that provide a protective barrier.
Step-by-step explanation:
The bacterial infection that affects sebaceous glands and leads to acne directly affects the stratum corneum layer of the epidermis. The stratum corneum is the most superficial layer of the epidermis and serves as a barrier to protect underlying tissues. It consists of dry, dead cells that shed periodically and prevent the penetration of microbes.