Final answer:
In SAS, the keyword to define the base dataset in PROC APPEND is 'BASE'. This is the dataset that will have additional data appended to it.
Step-by-step explanation:
In SAS, when using the PROC APPEND procedure, the keyword used to define the base dataset is BASE. This keyword is specified to indicate the dataset to which another dataset's observations will be appended. For example, in the code PROC APPEND BASE=work.main DATA=work.new;, the dataset work.main is the base dataset that will be appended with observations from the dataset work.new.