Question

The antidepressant class most used by clinicians to treat depression patients with PD is:

A) Non-selective MOA inhibitors
B) Tricyclic antidepressants
C) Serotonin and norepinephrine reuptake inhibitors
D) Selective serotonin reuptake inhibitors (SSRIs)

Answer 1

The most utilized class of antidepressants by clinicians to treat depression in patients with Parkinson's Disease are Selective serotonin reuptake inhibitors (SSRIs), such as Prozac, due to their efficacy and lower incidence of anticholinergic side effects.

Step-by-step explanation:

The antidepressant class most used by clinicians to treat depression patients with Parkinson's Disease (PD) is D) Selective serotonin reuptake inhibitors (SSRIs). SSRIs, such as clomiprimine, fluoxetine (Prozac), sertraline, and paroxetine, work by selectively blocking the reuptake of serotonin, thereby increasing the levels of serotonin in the central nervous system. This increase helps balance the neurotransmitters in the brain, which can alleviate symptoms of depression. Unlike tricyclic antidepressants or monoamine oxidase inhibitors, SSRIs typically have fewer anticholinergic side effects. It's important for clinicians to exercise caution when co-administering any drugs that affect serotonergic systems, especially with monoamine oxidase inhibitors, to avoid adverse interactions.