Final answer:
Mifepristone and ulipristal are emergency contraceptives that, when used, can cause temporary sterility, nausea, vomiting, and in rare cases, a significant reduction in blood cell counts. These effects are usually transient and reversible. The more severe toxicities described, such as fatalities from small intestine and blood system malfunction, are typically associated with high-dose radiation exposure, not the routine use of these medications.
Step-by-step explanation:
The question primarily concerns the pharmacological aspects of mifepristone and ulipristal, focusing on their toxicity profiles. When discussing the toxicity of these drugs, it is important to note the potential adverse effects and the clinical significance of these reactions. Both mifepristone and ulipristal act as emergency contraceptives, and their use can lead to several effects ranging from mild to severe depending on the dosage, individual sensitivity, and exposure.
Mifepristone is used to medically terminate early pregnancy and in smaller doses, it can serve as an emergency contraceptive. Its toxic effects can include temporary sterility, nausea, and vomiting, which are usually transient and not fatal. In more severe cases, related to higher exposures, patients may experience a significant reduction in blood cell counts, which can be a risk for hemorrhage and other complications.
Similarly, ulipristal used as an emergency contraceptive, might also lead to temporary adverse effects such as nausea and vomiting. While temporary sterility can occur, this effect is reversible and does not usually persist long-term. Concerning radiation exposure, effects mentioned such as lethargy, diarrhea or constipation, and possible rash indicate a radiation impact on the body and should not be confused with the toxicity of these medications. In severe instances like the ones indicated by an LD50/32 scenario, effects can include the malfunction of the small intestine and blood systems, leading ultimately to fatalities. However, this outcome is associated with high-dose radiation exposure and not typically linked to the pharmaceutical toxicity of mifepristone or ulipristal.