Final answer:
Selective Estrogen Receptor Modulators (SERMs) like Clomiphene can have negative side effects, including increased risk of stroke or heart attack, blood clots, breast cancer, ovarian cancer, endometrial cancer, gall bladder disease, and possibly depression. Estrogen supplementation through hormone replacement therapy (HRT) can prevent bone loss, but it also carries the risk of stroke or heart attack, blood clots, breast cancer, ovarian cancer, endometrial cancer, gall bladder disease, and possibly dementia.
Step-by-step explanation:
Selective Estrogen Receptor Modulators (SERMs) like Clomiphene can have negative side effects. These side effects include increased risk of stroke or heart attack, blood clots, breast cancer, ovarian cancer, endometrial cancer, gall bladder disease, and possibly depression.
Some side effects can be severe and irreversible, such as impaired heart function, testicular atrophy, and prostate enlargement. Estrogen supplementation in the form of hormone replacement therapy (HRT) can prevent bone loss, but it also has negative side effects, including increased risk of stroke or heart attack, blood clots, breast cancer, ovarian cancer, endometrial cancer, gall bladder disease, and possibly dementia.