Final answer:
Taking TB antibiotics can deplete pantothenic acid (vitamin B5).
Step-by-step explanation:
When taking TB antibiotics, the vitamin that can be depleted is pantothenic acid (vitamin B5). TB antibiotics such as isoniazid and hydrazoline may deplete this vitamin due to their structural resemblance to vitamin B6. Pantothenic acid is essential for the synthesis of coenzyme A and is involved in various metabolic processes in the body.