Final answer:
To avoid stomach irritation when taking NSAIDs, use the lowest effective dose for the shortest time, take with food or milk, and consider using protective agents like proton pump inhibitors or H2 blockers. Differentiate between NSAIDs and acetaminophen for liver safety, and use antacids or switch pain relievers if ulcers occur.
Step-by-step explanation:
When taking NSAIDs to decrease pain and inflammation, certain precautions should be taken to minimize stomach irritation. First, it's recommended to use the lowest effective dose for the shortest duration possible to reduce risks. Second, NSAIDs should be taken with food or milk to help protect the stomach lining. Additionally, the concurrent use of protective agents such as proton pump inhibitors (PPIs) or H2 blockers can help reduce the risk of gastrointestinal ulcers and bleeding, especially in high-risk individuals.
Those who have a history of stomach ulcers or are taking blood thinners should exercise extra caution. It is also important to understand the difference between NSAIDs and acetaminophen, which does not typically cause stomach irritation but can lead to liver damage in case of overdose. Lastly, antacids may offer symptomatic relief if stomach irritation occurs, but if NSAID-induced ulcers are present, switching to a different class of pain relievers and possibly antibiotics for H. pylori infections is advised.