Final answer:
Hepatic clearance can be classified in two ways: metabolism and renal excretion.
Step-by-step explanation:
Hepatic clearance can be classified in two ways: metabolism and renal excretion. Metabolism refers to the biochemical processes by which the liver breaks down drugs and other foreign substances, making them more easily eliminated from the body. Renal excretion, on the other hand, involves the elimination of drugs and their metabolites through the kidneys and subsequent excretion in urine.