Final answer:
Alexander the Great conquered Persia in 328 BCE, taking the Persian capital, Persepolis, in 330 BCE and claiming the throne after the assassination of Darius III.
Step-by-step explanation:
Alexander the Great conquered Persia in 328 BCE. This historical event marked the end of the mighty Persian Empire and the rise of Greek influence under Alexander's rule. After the death of Philip II, his son Alexander III, who would later become known as Alexander the Great, assumed the throne and set out to fulfill his father's plans of conquering Persia. He faced armies commanded by Darius III, which were mainly comprised of draftees from various parts of the Persian Empire.
Alexander's military prowess was showcased in pivotal battles such as those at Issus in 333 BCE and Gaugamela in 330 BCE. Ultimately, the Greek forces captured Persepolis, the Persian capital, in 330 BCE, signaling a decisive end to Persian resistance. Following the assassination of Darius III by his nobles, Alexander claimed the Persian throne and integrated some of the Persian customs into his court.