Final answer:
Hemodialysis and chelation therapy are the two most effective methods of increasing elimination of lithium.
Step-by-step explanation:
The two most effective methods of increasing elimination of lithium are hemodialysis and chelation therapy.
Hemodialysis is a process in which blood is filtered through a machine to remove waste products and excessive amounts of certain substances, such as lithium. During hemodialysis, blood is pumped out of the body, passes through a dialyzer, and is then returned to the body. This helps to remove lithium from the bloodstream and reduce its levels in the body.
Chelation therapy is a medical treatment that uses chelating agents to bind to heavy metals, such as lithium, and help remove them from the body. Chelating agents form chemical complexes with the metal ions, which can then be excreted through urine or feces. Chelation therapy can be administered orally or intravenously, depending on the specific situation.