Final answer:
Intradermal administration involves injecting medication between the epidermis and subcutaneous tissue.
Step-by-step explanation:
The administration of medication within the principle layer of the skin, between the epidermis and the subcutaneous tissue, is known as intradermal administration.
Intradermal administration involves injecting a small amount of medication into the dermis layer of the skin. This method is commonly used for diagnostic and allergy testing, as well as for administering certain vaccines.
During intradermal administration, a small needle is inserted at a shallow angle into the skin, creating a small raised bump or wheal. The medication is then injected into this wheal, allowing it to be absorbed into the surrounding tissues.