Question

High concentrations of ATP inhibit an enzyme involved in glycolysis.

(i) Describe how inhibition of glycolysis will affect the production of ATP by the electron transfer chain. (1)
(ii) Explain this effect. (3)
a) Inhibition of glycolysis has no effect on ATP production.
b) Inhibition of glycolysis reduces ATP production in the electron transport chain.
c) Inhibition of glycolysis enhances ATP production by the electron transport chain.
d) Inhibition of glycolysis results in the production of more ATP by the electron transport chain.

Answer 1

Inhibition of glycolysis reduces ATP production in the electron transport chain.

Step-by-step explanation:

Inhibition of glycolysis reduces ATP production in the electron transport chain.

Glycolysis is the initial step in cellular respiration, where glucose is broken down to produce pyruvate and a small amount of ATP. The subsequent steps of ATP production occur in the electron transport chain, where NADH and FADH2 produced in the citric acid cycle donate electrons to produce ATP by chemiosmosis.

Because high concentrations of ATP inhibit an enzyme involved in glycolysis, less pyruvate is produced, resulting in a lower supply of NADH and FADH2. As a result, the electron transport chain is impacted, leading to a reduced production of ATP.