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Hypervolomia has what effect on preload and what are the clinical manifestations?

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Final answer:

Hypervolemia increases preload and can lead to symptoms like edema, ascites, increased blood pressure, and heart failure. Restoring vascular homeostasis involves treating the underlying cause of the excessive fluid volume.

Step-by-step explanation:

Hypervolemia, or excessive fluid volume, leads to an increase in preload, which is the end-diastolic volume (EDV) present in the ventricles just before contraction. Due to the increased volume of blood, the heart's ventricles are stretched more, resulting in a higher preload. However, chronic hypervolemia can lead to heart failure where the heart's ability to compensate for the increased volume may be overwhelmed.

Clinical manifestations of hypervolemia include swelling or edema, ascites (accumulation of fluid in the abdominal cavity), increased blood pressure, and symptoms of heart failure such as shortness of breath and fatigue. In order to restore vascular homeostasis, it is critical to treat the underlying condition causing the hypervolemia, whether it be heart failure, kidney disease, or hormonal imbalances.

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