Question

This opioid, when used with MAOIs can cause CNS excitation expressing as agitation, hyperpyrexia, rigidity, or CNS depression expressing as hypotension, hypoventilation and coma?

Answer 1

Combining certain opioids with MAOIs can result in CNS excitation or depression.

Step-by-step explanation:

When the opioid is used with MAOIs, it can cause different central nervous system (CNS) effects. It can cause CNS excitation, which is expressed as agitation, hyperpyrexia (high body temperature), rigidity, or CNS depression, which is expressed as hypotension (low blood pressure), hypoventilation, and coma. These effects can occur when combining certain opioids, like morphine or oxycodone, with other medications called MAOIs.