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What effect does propofol have on CMRO2, CBF, ICP?

User Akalikin
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Final answer:

Propofol decreases CMRO2, reduces CBF, and helps maintain cerebral perfusion pressure.

Step-by-step explanation:

Propofol is a medication commonly used for anesthesia induction and maintenance. It has several effects on the body, including altering cerebral metabolic rate of oxygen consumption (CMRO2), cerebral blood flow (CBF), and intracranial pressure (ICP).



Propofol decreases CMRO2, which is the amount of oxygen the brain consumes to function. This is beneficial during anesthesia as it helps reduce the brain's demand for oxygen and protects brain cells from injury.



Propofol also decreases CBF, which is the amount of blood flow to the brain. By reducing CBF, propofol helps maintain cerebral perfusion pressure and decreases the risk of increased ICP.

User Porton
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