Final answer:
Systemic manifestations of acute kidney injury encompass a range of symptoms including metabolic imbalances, heart arrhythmias, and changes in urine output, which signify underlying complications in renal function and homeostasis.
Step-by-step explanation:
The systemic manifestations of acute kidney injury include metabolic acidosis, metabolic alkalosis, heart arrhythmias, uremia, fatigue, excessive urination, oliguria, and possible effects such as anemia, edema, and rising potassium levels. Acute kidney injury (AKI) results in various signs and laboratory findings indicative of renal failure.
When the kidneys are unable to function properly, it leads to an accumulation of waste and unbalanced electrolytes in the blood, causing systemic complications. Effects on cardiovascular health, alterations in fluid and electrolyte balance, changes to blood acid levels, and the potential for infections such as sepsis are common with significant kidney impairment.