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Severe diabetic ulcer w/ signs of systemic inflammatory response which IV antibiotics?

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Final answer:

The choice of IV antibiotics for severe diabetic ulcers with signs of systemic inflammatory response depends on the specific bacteria causing the infection and their sensitivity to different antibiotics. Broad-spectrum antibiotics such as Vancomycin, Piperacillin-tazobactam, Ceftriaxone, and Meropenem are commonly used initially. The final decision should be made by a healthcare professional based on culture and sensitivity testing.

Step-by-step explanation:

When treating a severe diabetic ulcer with signs of systemic inflammatory response, the choice of IV antibiotics will depend on the specific bacteria causing the infection and their sensitivity to different antibiotics. In such cases, broad-spectrum antibiotics are commonly used initially to cover a wide range of potential pathogens. Some commonly used IV antibiotics for severe diabetic ulcers include:

  • Vancomycin: This is a glycopeptide antibiotic that is effective against many gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA).
  • Piperacillin-tazobactam: This is a combination antibiotic that covers a broad range of gram-negative bacteria.
  • Ceftriaxone: This is a third-generation cephalosporin antibiotic that is effective against many gram-negative bacteria.
  • Meropenem: This is a carbapenem antibiotic that covers a wide range of bacteria, including gram-negative and gram-positive bacteria that are resistant to other antibiotics.

It is important to note that the choice of antibiotics should be made by a healthcare professional based on the specific circumstances and the results of culture and sensitivity testing.

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