Final answer:
The first-line treatment for hypotension in septic shock involves prompt administration of intravenous fluids, vasopressors to support blood pressure, and appropriate antibiotics, such as tigecycline for drug-resistant bacteria, and supportive treatments like dialysis as needed.
Step-by-step explanation:
The first-line treatment for patients with hypotension (HoTN) in septic shock typically involves aggressive management aimed at stabilizing blood pressure and combating infection. Initial interventions include the immediate administration of intravenous fluids to enhance circulation and blood pressure, followed by medications to support blood pressure such as vasopressors.
Antibiotics play a critical role in targeting the underlying infection causing sepsis. For drug-resistant bacterial infections, medications such as tigecycline may be used. In severe cases where organ function is compromised, supportive treatments like dialysis could be necessary.