Final answer:
11 beta hydroxylase deficiency results in an increase in the levels of acetylcholine, cortisol, histamine, plasma dopamine -ß-hydroxylase (DBH), and urinary polyamines.
Step-by-step explanation:
In 11 beta hydroxylase deficiency, there is an increase in the levels of acetylcholine, cortisol, histamine, plasma dopamine -ß-hydroxylase (DBH), and urinary polyamines. Acetylcholine, cortisol, and histamine are neurotransmitters and hormones that play important roles in various physiological processes. Plasma dopamine -ß-hydroxylase (DBH) is an enzyme involved in the metabolism of catecholamines. Urinary polyamines are essential growth factors for the liver.
This increase in these substances is due to the enzymatic defect caused by 11 beta hydroxylase deficiency. 11 beta hydroxylase is responsible for converting 11-deoxycortisol to cortisol in the adrenal glands. When this enzyme is deficient, there is an accumulation of 11-deoxycortisol and other intermediate hormones, leading to the increased levels of acetylcholine, cortisol, histamine, plasma dopamine -ß-hydroxylase (DBH), and urinary polyamines.
Overall, 11 beta hydroxylase deficiency results in an imbalance of these substances, which can have various effects on the body depending on the specific context and severity of the deficiency.