Final answer:
Amiodarone is the drug that increases serum levels of digoxin and can lead to toxicity if used concurrently, necessitating close monitoring and potential digoxin dose adjustment.
Step-by-step explanation:
The drug that increases the serum levels of digoxin and can lead to digoxin toxicity if given concurrently is amiodarone, an antiarrhythmic medication. Amiodarone interacts with digoxin by inhibiting its clearance and increasing its serum concentration. This interaction necessitates close monitoring of digoxin levels and may require a reduction in the digoxin dose to avoid toxicity. Symptoms of digoxin toxicity include nausea, vomiting, dizziness, vision changes, and cardiac arrhythmias.
The drug that increases the serum levels of digoxin and can lead to digoxin toxicity when given concurrently with digoxin is Amiodarone. Amiodarone is an antiarrhythmic medication used to treat abnormal heart rhythms. It inhibits the P-glycoprotein transporter, which is responsible for eliminating digoxin from the body.