Final answer:
Chronic use of nonsteroidal anti-inflammatory drugs (NSAIDs) can lead to an increased risk of gastrointestinal ulcers and bleeds, as well as kidney damage.
Step-by-step explanation:
Chronic use of nonsteroidal anti-inflammatory drugs (NSAIDs) can have several undesirable consequences on the body. One of the most common is an increased risk of gastrointestinal ulcers and bleeds. NSAIDs inhibit the production of prostaglandins, which play a role in protecting the stomach lining. Without these protective prostaglandins, the stomach is more susceptible to damage and irritation, leading to ulcers and bleeding.
In addition, long-term use of NSAIDs can also lead to kidney damage. NSAIDs can affect blood flow to the kidneys and disrupt normal kidney function, which can result in kidney disease over time.
Overall, while NSAIDs provide relief from pain and inflammation, chronic use of these drugs can have significant negative effects on the gastrointestinal system and the kidneys.