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A client with cystic fibrosis is taking pancreatic enzymes. The nurse should administer this medication:

Once per day in the morning
Three times per day with meals
Once per day at bedtime
Four times per day

1 Answer

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Final answer:

Pancreatic enzymes for a client with cystic fibrosis should be taken three times per day with meals to aid in digestion. These enzymes work in the small intestine to digest nutrients properly, especially since the pancreas of someone with cystic fibrosis cannot produce sufficient natural enzymes.

Step-by-step explanation:

The student asked how often a client with cystic fibrosis should take pancreatic enzymes. This medication is essential for patients with cystic fibrosis because their pancreas does not secrete enough enzymes naturally due to blockages in the pancreatic ducts caused by thick mucus. The lack of enzymes leads to problems with digestion and absorption of nutrients, particularly fats, which is why enzyme supplementation is essential.


Pancreatic enzymes should be taken as prescribed, which is commonly with every meal to aid in the digestion of food. Therefore, the correct administration would typically be three times per day with meals. This ensures that the enzymes are present in the small intestine when food arrives there, allowing for the proper digestion of nutrients. These enzymes include pancreatic amylase, which completes the chemical digestion of carbohydrates. It is important to note that the small intestine secretes mucus to protect itself from the active enzymes that have been activated by an enzyme in its wall, removing the amino acid "muzzles" from the pancreatic enzymes.


While the pancreatic enzyme supplementation is crucial, it is just one part of the comprehensive management for cystic fibrosis, which may also include antibiotics, pulmonary rehabilitation, and other treatments aimed at maintaining lung function and managing other symptoms of the disease. However, for the specific question of when the pancreatic enzymes should be taken, the answer is during meals to optimize the digestion process.

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