Question

What problem, noted in the client's history, is important for the nurse to be aware of prior to administration of a newly prescribed selective serotonin reuptake inhibitor (SSRI)?

Answer 1

It's important for the nurse to know of any MAOI use prior to administration of an SSRI due to the risk of serotonin syndrome. Familiarity with the full medication regimen is essential to prevent interactions with other serotonergic drugs.

Step-by-step explanation:

Before administering a selective serotonin reuptake inhibitor (SSRI) to a client, it is crucial for the nurse to be aware of any history of the client taking monoamine oxidase inhibitors (MAOIs). MAOIs are a class of antidepressants that can lead to serious interactions when combined with SSRIs, due to the potential for serotonin syndrome - a condition characterized by high levels of serotonin in the brain that can be life-threatening. SSRI drugs, like Prozac, Paxil, and Zoloft, inhibit the reuptake of serotonin, increasing its levels in the central nervous system and alleviating symptoms of depression and other mood disorders.

Additionally, the nurse should be informed about the client's entire medication regimen to avoid interaction with other drugs affecting the serotonergic system. These can include over-the-counter medications, herbal supplements, and other prescribed drugs with serotonergic properties. SSRI treatment requires careful monitoring, particularly in the initial weeks, and awareness of all individual client factors, including their medication history.