Final answer:
Each nephron loop has an ascending limb that extends from the cortex to the medulla and a descending limb that returns back into the renal cortex.
Step-by-step explanation:
Each nephron loop has two limbs, an ascending limb that extends from the cortex to the medulla and a descending limb that returns back into the renal cortex. In juxtamedullary nephrons, these limbs extend deep into the medulla, while in cortical nephrons, they do not extend beyond the cortex.