Final answer:
The controlled substance among the given medications is Hydrocodone with APAP, which is an opioid pain reliever and classified as a Schedule II drug due to its high potential for abuse and dependence.
Step-by-step explanation:
The correct option : E
Explanation: Controlled substances are drugs that have potential for abuse and dependence, and they are strictly regulated by laws. Hydrocodone is an opioid pain medication often combined with acetaminophen (APAP), and it is classified as a Schedule II controlled substance in the United States. This means it has a high potential for abuse, which may lead to severe psychological or physical dependence.
Other medications listed, like Amlodipine is a calcium channel blocker, Atenolol is a beta-blocker, Trazodone is an antidepressant, and Furosemide is a diuretic. These medications are not categorized as controlled substances because they have lower potential for abuse and dependence. They are used to treat various medical conditions such as hypertension (high blood pressure), heart conditions, depression, and edema respectively. It is important to use these medications as prescribed by healthcare professionals, and Hydrocodone should be used with caution due to its nature as a controlled substance.