Final answer:
A Cerebrovascular accident (stroke) is the condition most likely to result in unequal pupils, known as anisocoria, since it can affect the neural pathways that control pupil size.
Step-by-step explanation:
The condition most likely to result in unequal pupils, also known as anisocoria, is D. Cerebrovascular accident (stroke). When a stroke occurs, it can affect the pathways that control the muscles around the pupils, leading to unequal pupil sizes. Conditions like heart attacks or diabetic coma may not specifically cause anisocoria unless they secondarily lead to a stroke or another form of brain injury. Drug overdose could potentially result in anisocoria as well, depending on the substance and its effects on the brain. The sympathetic activation that occurs during the fight-or-flight response, like the one experienced by a student after a car accident, includes pupil dilation as well as increased heart rate and rapid breathing but does not necessarily result in unequal pupils unless there is an underlying neurological injury.