Question

Following an injury, scar formation builds on the granulation tissue framework. Proliferation of fibroblasts occur with the assistance of which growth factors that have been released from enothelial and inflammatory cells at the site of injury? Select all that apply.

Answer 1

Platelet-derived growth factor (PDGF), Transforming growth factor-beta (TGF-beta), and Fibroblast growth factor (FGF) are the growth factors released from endothelial and inflammatory cells that assist in the proliferation of fibroblasts during scar formation.

Step-by-step explanation:

The growth factors released from endothelial and inflammatory cells at the site of injury assist in the proliferation of fibroblasts during scar formation. These growth factors include:

1. Platelet-derived growth factor (PDGF): Stimulates the division and migration of fibroblasts
2. Transforming growth factor-beta (TGF-beta): Promotes collagen production and tissue remodeling
3. Fibroblast growth factor (FGF): Plays a role in angiogenesis and stimulates the proliferation of fibroblasts