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Normal MCV, ↑LDH, ↑indirect bilirubin, ↓haptoglobin

w/ Splenomegaly, +FH, bilirubin gallstones, ↑MCHC?

User Vitaliytv
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Final answer:

This set of symptoms is consistent with a condition called hereditary spherocytosis, a genetic disorder characterized by spherical-shaped red blood cells, increased destruction of red blood cells, anemia, jaundice, and splenomegaly.

Step-by-step explanation:

This set of symptoms is consistent with a condition called hereditary spherocytosis. Hereditary spherocytosis is a genetic disorder characterized by the presence of spherical-shaped red blood cells, which are more fragile and easily destroyed. The increased destruction of red blood cells leads to anemia, jaundice, and an enlargement of the spleen (splenomegaly).

The elevated LDH (lactate dehydrogenase) and indirect bilirubin levels are indicative of increased red blood cell breakdown. The decreased haptoglobin level is also related to red blood cell destruction, as haptoglobin binds free hemoglobin released from the breakdown of red blood cells.

In addition, the presence of bilirubin gallstones suggests pigment stones, which are formed from unconjugated bilirubin. The increased MCHC (mean corpuscular hemoglobin concentration) is a result of the dehydration of red blood cells due to their spherical shape.

User Vivex
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