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Bump in creatinine 48-72hrs s/p cardiac cath or contrast CT scan?

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Final answer:

An elevation in creatinine levels following a cardiac catheterization or contrast CT scan may indicate contrast-induced nephropathy, a type of acute kidney injury. This condition necessitates close monitoring of kidney function and may require specific treatment to manage and prevent long-term damage.

Step-by-step explanation:

Creatinine Increase After Cardiac Procedures

An increase in creatinine levels 48-72 hours after a cardiac catheterization or a contrast CT can indicate a condition known as contrast-induced nephropathy (CIN), which is a form of acute kidney injury (AKI). CIN is characterized by a relative increase in serum creatinine by 25% or an absolute increase of more than 0.5 mg/dL within 48-72 hours after exposure to contrast medium.

The risk factors for CIN include pre-existing renal impairment, diabetes, heart failure, and the use of large volumes of contrast agent. Treatment typically involves hydration and potentially the avoidance or limitation of nephrotoxic substances. Monitoring kidney function through creatinine levels and urine output is essential in detecting and managing this condition. In severe cases, CIN can result in long-term or permanent kidney damage.

According to the provided criteria, renal injury is indicated by a creatinine level 2.0 times baseline or urine production <0.5 ml/kg for 12 hours. Renal failure is marked by a creatinine level 3.0 times baseline, creatinine >355 mmol/l with a rise of >44, or urine output below 0.3 ml/kg for 24 hours. Persistent renal failure lasting more than four weeks is classified as a complete loss of kidney function.

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