The release of antidiuretic hormone (ADH) is triggered by elevated blood osmolarity, significant loss of blood volume, or dehydration and is secreted from the posterior pituitary gland. Alcohol can inhibit its release, while conditions like diabetes insipidus indicate underproduction of ADH.
The conditions that cause the release of antidiuretic hormone (ADH), also known as vasopressin, include an upsurge in blood plasma osmolarity, significant loss of blood volume, or dehydration. This hormone is produced in the hypothalamus and stored and released from the posterior pituitary gland. ADH acts on the kidneys to reabsorb water, thus reducing urine output and helping to preserve the body's water balance.
Alcohol can inhibit the release of ADH, leading to increased urine production. Conditions such as diabetes insipidus involve underproduction of ADH, resulting in chronic dehydration due to decreased water reabsorption by the kidneys. Elevated blood osmolarity above 300 mOsm/L or physiological stress also triggers the secretion of ADH to restore fluid balance.