Final answer:
The best initial nursing action would be to initiate seizure precautions.
Step-by-step explanation:
The best initial nursing action for a client experiencing withdrawal from the benzodiazepine alprazolam and demonstrating severe agitation and tremors would be to initiate seizure precautions.
Withdrawal from benzodiazepines can cause hyperactivity of the central nervous system, leading to seizures. By initiating seizure precautions, such as padding the client's bed and removing any potentially harmful objects from their surroundings, the nurse can ensure the client's safety during this withdrawal period.
Administering naloxone per PRN protocol would not be appropriate in this case, as naloxone is used to reverse opioid overdose, not benzodiazepine withdrawal. Obtaining a serum drug screen can provide information about the presence of benzodiazepines in the client's system, but it is not the best initial action to address the agitation and tremors. Instructing the family about withdrawal symptoms is important for their understanding and support, but it is not the best initial action to address the client's current condition.