Question

What is the onset and duration of Glucagon when administered intravenously (IV) for gastrointestinal (GI) x-rays?

A) Onset: 30-60 minutes, Duration: 6-8 hours
B) Onset: 5-10 minutes, Duration: 30-60 minutes
C) Onset: 2-4 hours, Duration: 8-12 hours
D) Onset: 15-30 minutes, Duration: 1-2 hours
E) Onset: 1-2 hours, Duration: 4-6 hours

Answer 1

Option D. The onset of glucagon administered intravenously for GI x-rays is 15-30 minutes, and the duration is 1-2 hours.

Step-by-step explanation:

When glucagon is administered intravenously (IV) for gastrointestinal (GI) x-rays, the onset and duration depend on the individual's tolerance to glucagon. In a glucagon tolerance test, the blood glucose is measured in fasting condition, and then a dose of 30 µg of glucagon per kg of body weight is given intravenously. Blood glucose is estimated every half an hour after injection.

The ability to tolerate glucagon is assessed based on the individual's blood glucose levels over time. In general, the onset of glucagon's effect is around 15-30 minutes after administration. The duration of its action is approximately 1-2 hours. The onset of glucagon administered intravenously for GI x-rays is 15-30 minutes, and the duration is 1-2 hours.