Final answer:
Thiazide diuretics work in the distal convoluted tubule by preventing reabsorption of sodium.
Step-by-step explanation:
The class of diuretics that works in the distal convoluted tubule of the kidney by preventing reabsorption of sodium is thiazide diuretics. Thiazide diuretics act by inhibiting the sodium-chloride symporter in the distal convoluted tubule, which reduces sodium reabsorption and therefore increases the excretion of sodium and water, leading to increased urine production.
For example, the drug hydrochlorothiazide is a commonly used thiazide diuretic that is prescribed to treat hypertension (high blood pressure) and edema (fluid retention). By preventing the reabsorption of sodium in the distal convoluted tubule, it helps to reduce excess fluid in the body and lower blood pressure.
Therefore, the correct answer is A) thiazide diuretics.