Question

"Patient: 42-year-old Caucasian female

Chief complaint: ""I've been having difficulty swallowing.""
Background: No relevant patient history.
Current Findings: You notice ptosis of both eyelids and some slurring of words. The patient says that her arms feel weak and her vision is sometimes blurry. She says her symptoms tend to get worse at bedtime. You tell the patient she might have myasthenia gravis.

Which of the following is true about the cellular component affected by your patient's disease
a. When epinephrine binds to it, second messenger is activated
b. It is a component of the nucleus
c. When acetylcholine binds to it, membrane will become depolarized
d. Is a nicotinic receptor
e. Is a ligand gated ion channel
f. It is located in the mitochondrial membrane"

Answer 1

In myasthenia gravis, the acetylcholine receptor at the neuromuscular junction is a nicotinic receptor and ligand-gated ion channel that becomes depolarized upon acetylcholine binding.

Step-by-step explanation:

Myasthenia gravis is an autoimmune disorder where antibodies target and block the function of the acetylcholine receptors at the neuromuscular junction, inhibiting muscle contraction. The cellular component affected by the disease in the patient's case is an acetylcholine receptor, which when acetylcholine binds to it, leads to depolarization of the membrane.

Hence, the true statements about the cellular component affected by myasthenia gravis are that it becomes depolarized when acetylcholine binds to it, it is a nicotinic receptor, and it is a ligand-gated ion channel.