Question

"Patient: 23-year-old male

Chief complaint: ""I've been very tired lately and cannot sleep.""
Background: Diagnosed with a rare genetic disorder, a point mutation that leads to a Glu to Arg substitution in the pore of a sodium channel.
Current Findings: None at this time.

What is likely the effect on sodium transport?
a. Sodium influx into the cell will be slower
b. Sodium outflow from the cytoplasm will be slower
c. Sodium outflow from the cytoplasm will be faster
d. Sodium influx into the cell will be faster"

Answer 1

The effect of the Glu to Arg substitution in the pore of a sodium channel in a patient with a rare genetic disorder is that sodium influx into the cell will be slower.

Step-by-step explanation:

The effect of the Glu to Arg substitution in the pore of a sodium channel in a patient with a rare genetic disorder is that sodium influx into the cell will be slower. In healthy individuals, sodium channels allow sodium ions to flow into the cell. However, the point mutation in the sodium channel in this patient hinders the movement of sodium ions into the cell, leading to a slower influx of sodium.

Answer 2

The effect on sodium transport in a person with a Glu to Arg substitution in the pore of a sodium channel is that sodium influx into the cell will be slower.

Step-by-step explanation:

In a person with a rare genetic disorder that leads to a Glu to Arg substitution in the pore of a sodium channel, the effect on sodium transport would be that sodium influx into the cell will be slower (option a).

This is because the point mutation in the sodium channel affects its function, leading to a slower movement of sodium ions into the cell.