Question

Which information indicates the nurse has a good understanding about the mechanism of action for maraviroc?

a) Inhibits the insertion of viral DNA into the host cell's human DNA
b) Prevents protease enzyme from cutting human immunodeficiency virus (HIV) into the proper length
c) Blocks the C-C chemokine receptor type 5 (CCR5) receptor on CD4+ T cells
d) Binds directly to the HIV-1 enzyme reverse transcriptase

Answer 1

The correct information that indicates the nurse understands the action of maraviroc is that it blocks the CCR5 receptor on CD4+ T cells, classifying it as a CCR5 antagonist in the anti-HIV drug regimen. Maraviroc is not associated with inhibiting viral DNA integration, protease activity, or reverse transcriptase.

Step-by-step explanation:

The nurse demonstrates a good understanding of the mechanism of action for maraviroc if they state that maraviroc blocks the C-C chemokine receptor type 5 (CCR5) receptor on CD4+ T cells. Maraviroc belongs to a class of anti-HIV drugs known as CCR5 antagonists which prevent the HIV virus from entering CD4 cells. By doing so, it interferes with the HIV infection cycle and stops the virus from replicating within the host's cells. It is important to note that maraviroc is not involved in the inhibition of viral DNA insertion, protease enzyme activity, or the reverse transcriptase enzyme, which are targeted by other types of antiretroviral drugs such as integrase inhibitors, protease inhibitors, and reverse transcriptase inhibitors, respectively.