Question

______ is an alternative sweetener that was once thought to cause bladder cancer, but now is considered safe when consumed in typical amounts.

Answer 1

Saccharin was once believed to cause bladder cancer but is now considered safe for typical use, following extensive research and no evidence of harm to humans.

Step-by-step explanation:

The alternative sweetener that was once thought to cause bladder cancer but is now considered safe for consumption in moderate amounts is saccharin. In the 1970s, studies suggested that saccharin could raise the risk of bladder cancer, leading the US Food and Drug Administration (FDA) to propose a ban. However, due to public opposition and further research, saccharin remained on the market with a required warning label. As of today, that warning is no longer necessary, and saccharin is regarded as safe when consumed in typical amounts.

Originally, saccharin faced scrutiny after a study showed an increased incidence of bladder cancer in rats, but no evidence has shown a carcinogenic effect on humans when used as intended. Moreover, saccharin is now widely used as an artificial non-caloric sweetener, especially in diet beverages for people with diabetes or those managing their weight. The historical context of saccharin's regulatory status highlights the evolving nature of scientific understanding and risk assessment in food safety.