Final answer:
Nystatin is not absorbed systemically. Oral nystatin does not work systemically, but there are other antifungal drugs that do.
Step-by-step explanation:
Nystatin is typically used as a topical treatment for yeast infections of the skin, mouth, and vagina, but may also be used for intestinal fungal infections. It is not absorbed systemically, meaning it does not enter the bloodstream and travel throughout the body to work on systemic infections. On the other hand, some drugs are designed to be absorbed systemically, such as amphotericin B. This drug is used for systemic fungal infections like aspergillosis and cryptococcal meningitis. So, while oral nystatin does not work systemically, there are other antifungal drugs, like amphotericin B, that are designed to work systemically.