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In plasma cell dyscrasias, the plasma cells may be greatly increased in circulation and/or may completely infiltrate the bone marrow, as seen in:

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In plasma cell dyscrasias, such as multiple myeloma, the plasma cells can greatly increase in circulation or infiltrate the bone marrow. This leads to the production of abnormal antibodies known as monoclonal proteins or M proteins. These abnormal plasma cells can be detected through tests like protein electrophoresis.

Step-by-step explanation:

In plasma cell dyscrasias, the plasma cells can be greatly increased in circulation and/or completely infiltrate the bone marrow. This is observed in certain conditions such as multiple myeloma, leukemia, and Hodgkin's disease. In multiple myeloma, there is excessive division of lymphocytes producing abnormal antibodies called monoclonal proteins or M proteins. These abnormal plasma cells can be detected through tests like protein electrophoresis and are associated with elevated serum protein levels and a distinct band in the gamma globulin region of the gel.

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