Question

The nurse is caring for a depressed client with a new prescription for an SSRI antidepressant. In reviewing the admission history and physical, which of the following should prompt questions about the safety of this medication?

A) History of obesity
B) Prescribed use of an MAO inhibitor
C) Diagnosis of vascular disease
D) Takes antacids frequently

Answer 1

The nurse should question the safety of prescribing SSRIs to a depressed client who is also taking MAO inhibitors due to the potential interaction and risk of serotonin syndrome.

Step-by-step explanation:

The nurse should question the safety of prescribing selective serotonin reuptake inhibitors (SSRIs) to a depressed client who is also prescribed monoamine oxidase inhibitors (MAO inhibitors). MAO inhibitors should not be taken with SSRIs due to their interactions.

When MAO inhibitors are taken with SSRIs, it can lead to a potentially dangerous condition known as serotonin syndrome. Serotonin syndrome can cause symptoms such as high blood pressure, fever, agitation, hallucinations, and rapid heartbeat.

Therefore, it is crucial to avoid combining MAO inhibitors with SSRIs to ensure the safety of the patient.