Final answer:
There are several medications that can increase clearance and lower plasma levels. Examples include clofibrate, nicotinic acid, bile sequestrants, and thyroid active substances.
Step-by-step explanation:
There are several medications that can increase clearance and lower plasma levels. One example is clofibrate, a drug used to treat hyperlipoproteinemia. Clofibrate is a chlorophenoxy butyrate compound that can reduce plasma lipid levels and increase the rate at which these lipids are cleared from the body. Another medication is nicotinic acid and its esters, which also lower plasma lipid levels by increasing lipid clearance.
Bile sequestrants are another type of medication that can increase clearance and lower plasma levels. These drugs bind to bile acids in the intestine, preventing their reabsorption and promoting their excretion. This can effectively reduce plasma cholesterol levels.
Thyroid active substances are also known to increase clearance and lower plasma levels. These substances, such as levothyroxine, increase the metabolic rate of the body, leading to increased clearance of various substances, including medications, and lower plasma levels.